Nucleophilic Substitution Reaction
Mechanism of bimolecular (SN2) nucleophilic substitution [Mechanism & Kinetics]
An SN2 reaction proceeds with complete stereo chemical inversion.
SN2 reaction decreases with stearic hinderance and increases by presence of nonprotic solvent for example DMF and DMSO. SN2 reaction decreases in the presence of protic solvent like CH3OH, C2H5OH, HF etc.
As the size of alkyl group increases than chemical reactivity towards SN2 decreases.
As the size of alkyl group increases sterichindrance comes into play so reactivity decreases.